Key Projects

New Approaches towards Research, Diagnosis and Therapy: funding programme to enable scientists’ research projects in the field of medicine that promise a breakthrough in the sense of developing a new therapeutical approach or the revision of generally accepted textbook knowledge.
Research at Internal Medicine II Clinic, Uniklinik Freiburg

Applications can be submitted at any time.

The Foundation’s aim with this funding measure is to find projects that have the potential to lead to fundamental discoveries that are groundbreaking for an entire field of research. This could be, for example:

  • evidence of a causal connection that was previously lacking,
  • testing of a previously non-existent or unworkable hypothesis,
  • questioning of a previously generally accepted theory, a “proof of principle” or a “first-in-man” examination of an innovative intervention approach,
  • or even a clinical trial that has the potential to significantly transform guidelines (with the exception of phase III pharmaceutical trials).

It is in the nature of going beyond the boundaries of previous limits of knowledge that such key projects can often not be assigned to any particular field or any thematically defined call for applications.

 

Portrait Anne Asschenfeldt
Anne Asschenfeldt
Scientific Funding: Ongoing Project Funding and Fellowships

Addressees Eligible to Apply
Applications can be made by scientists who have gained international recognition in their area of research and who have had outstanding publications in relevant fields. The applicants should provide convincing evidence that their work group is particularly suited – also in the competitive international context – to solving the problem at hand through the interplay between expertise, preparatory work or even infrastructure.

Both human and material resources may be applied for as necessary and scientifically justified for implementation of the planned project. The funds shall be allocated in a two-stage procedure. Prior to the time-consuming formulation of a full application, a draft proposal should be submitted first. The topicality and potential of the project idea as a key project shall be evaluated based on this draft.

Project managers of an EKFS funding project that is currently ongoing shall only be eligible to make a new application after completion and publication of the results of that project.

Downloads

Funding of Groundbreaking Key Projects
for the preparation of outlines towards application for a key project
Template
Declaration of consent of Applicant(s) for storage of data [PDF]
Terms and Conditionspdf / 138.15 KB
of Approval (in German)

Overview of key projects running since 2019

Nadine Gehrke, University Medical Center Mainz

Key project: "Role of hepatic IL-1R1 in inflammatory hepatocarcinogenesis" (2019)

Here you can get further information.


A brief description can be found on our website in the menu Currently Funded Projects.

Benjamin Mordmüller, University Hospital Tuebingen

Key project: "Inducing blood stage immunity by repeated Plasmodium falciparum sporozoite infection" (2019)

Verena Gaidzik, University Hospital Ulm

Key project: "Monitoring of therapy effects and detection of minimal residual disease (MRD) in adult acute myeloid leukemia (AML) with DNMT3A mutation within the framework of innovative study concepts of the AMLSG (AMLSG 09-09, AMLSG 12-09 and ALMSG 16-10)" (2019)

Toralf Reimer, University Hospital Rostock

Key project: "Omission of sentinel lymph node biopsy in triple-negative and HER2-positive breast cancer patients with radiologic and pathologic complete response in the breast after neoadjuvant systemic therapy: a single-arm, prospective surgical trial (EUBREASR-01 trial)" (2020)

Here you can get further information.

A brief description can be found on our website in the menu Currently Funded Projects.

Christian Schachtrup, Albert-Ludwigs-Universität Freiburg

Key project: "Role of the blood-derived coagulation factor Fibrinogen on Fibrotic Scaring in CNS disease" (2020)

Here you can get further information.

A brief description can be found on our website in the menu Currently Funded Projects.

Jonas Neher, German Center for Neurodegenerative Diseases (DZNE) e.V. and Hertie Institute for Clinical Brain Research

Key project: "The impact of peripheral inflammation on the human brain’s immune response and its role in Alzheimer’s disease" (2020)
 

A brief description can be found on our website in the menu Currently Funded Projects.

Daniel Kotlarz, Dr. von Hauner Children’s Hospital, Department of Pediatrics, University Hospital, Ludwig-Maximilians-Universität München

Key Project: "Monogenic CD33 deficiency as cause of pediatric inflammatory bowel disease – A model to explore mechanisms and therapeutic targets for inflammatory and hematological disorders" (2021)

A brief description can be found on our website in the menu Currently Funded Projects.

Georg Häcker, Institute of Microbiology and Hygiene, Universitätsklinikum Freiburg

Key Project: "DNA damage response by caspase-activated DNAse (CAD): a physiological process with pathophysiological potential?"

A brief description can be found on our website in the menu Currently Funded Projects.

Michael Arzt, University Hospital Regensburg

Key Project: "Effects of adaptive servoventilation on ventricular arrhythmias in heart failure patients with either obstructive or central sleep apnea – a substudy of the ADVENT-HF trial"

A brief description can be found on our website in the menu Currently Funded Projects.

Joachim Andrassy, Klinikum der Universität München

Key Project: "Study of biliary microbiome in liver transplantation (SMILE)"

A brief description can be found on our website in the menu Currently Funded Projects.

Christian Beste, TU Dresden, Universitätsklinikum Carl Gustav Carus

Key Project: "From phenomena to theory-guided mechanisms: changing perspectives on ADHD"

A brief description can be found on our website in the menu Currently Funded Projects.