Project partner:
Deutsches Forschungszentrum für Künstliche Intelligenz (DFKI) - Forschungsbereich Smarte Daten & Wissensdienste
Klinik für Urologie des Universitätsklinikums Tübingen
Zentrum für Uro-Onkologie des Ordensklinikums Linz, Tumorzentrum Oberösterreich
Project description:
Since July 1, 2025, Professor Constanze Schmidt has been the new Director of the Clinic for Cardiology and Pneumology at the University Medical Center Göttingen (UMG) – and the only woman to currently hold a chair in cardiology in Germany. The physician is researching atrial cardiomyopathy, a pathological alteration of the atria that can lead to atrial fibrillation and strokes.
Breast cancer is the most common cancer in women and most cases can be cured. Still, around 10% of patients experience a local relapse after initial treatment. Treating a relapse is challenging due to previous therapies. A new study aims to find the best way to re-irradiate in such cases—especially when trying to preserve the breast. The study will look at side effects, quality of life, and treatment success. Based on the results, clear recommendations will be developed to help more women make informed and personalized decisions if their cancer returns.
Bad Homburg v. d. Höhe, 21 August 2025 – The Else Kröner-Fresenius-Stiftung (EKFS) will provide a total of 1.7 million euros in funding for four digital health projects in countries with limited resources. With its special “Digital Health” call for proposals, the EKFS aims to encourage the practical implementation of digital technologies, such as software solutions and digital devices, as well as to assess their scalability with a large number of users.
*v.l.n.r.: Prof. Heiko Witt / Pädiatrische Ernährungsmedizin, Prof. Alexander Bartelt / Translationale Ernährungsmedizin, Prof. Katharina Timper / Klinische Ernährungsmedizin, Prof. Martin Klingenspor / Molekulare Ernährungsmedizin, Dr. Ulrike Schneider / Geschäftsführung EKFZ, Prof. Hans Hauner / Seniorprofessor für Ernährungsmedizin der EKFS
Liver diseases affect 29 million people in Europe. Under stress from factors like aging, alcohol, and high-fat diets, liver cells can stop working properly, entering a state called senescence. This leads to fat build-up and inflammation, worsening a mild condition to a severe disease state called MASH. Our research indicates that the cellular senescence is common and worsens liver issues by attracting immune cells and causing fibrotic scarring.
Proliferative vitreoretinopathy (PVR) is characterized by the formation of scar tissue at the interface between vitreous and retina and represents the leading cause for failure of retinal detachment surgery. One of the reasons for this is the currently insufficient understanding of disease progression. Due to their proximity to lesion sites, vitreous cells, so-called hyalocytes, may contribute to scar formation. Technical advances of cell sorting and transcriptome analysis have enabled us to characterize this cell type as members of the innate immune system.
