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Schema zur Entfernung von Tumorzellen durch den programmierten Zelltod (Apoptose) und einiger Faktoren, die dies beeinflussen können.
Projekt

Therapeutische Nutzung des programmierten Zelltods zur Lungenkrebsbehandlung

Institution: Molekulare Pathologie, Institut für Pathologie & Translationale Genomik, Uniklinik Köln
Applicant: Dr. med. Johannes Brägelmann

DNA Fäden im Reagenzglas. Neben der Abfolge der DNA Bausteine (Basen) spielen chemische Veränderungen der DNA Stränge eine wichtige Rolle, wie aktuell erforscht wird.
Projekt

Molekulare Präzisionsmedizin bei Dilatativer Kardiomyopathie

Institution: Universitätsklinikum Heidelberg
Applicant: Benjamin Meder

Liquid Biopsy has evolved as a promising approach for noninvasive cancer detection and monitoring.
Projekt

Circulating tumor DNA for noninvasive disease profiling and monitoring in patients with primary CNS lymphoma

Institution: University Medical Center Freiburg, Department of Hematology, Oncology, and Stem Cell Transplantation
Applicant: Dr. Florian Scherer

Konzept der primären, altersbedingten und sekundären, erkrankungsbedingten Presbyphagie.
Projekt

Biologische Determinanten und neuronale Kompensationsmechanismen der Presbyphagie

Institution: Klinik für Neurologie mit Institut für Translationale Neurologie, Universitätsklinikum Münster
Applicant: PD Dr. med. Sonja Suntrup-Krüger

Frank Giordano
Projekt

Boosting Twice: Systemische Immuneffekte nach Hochdosis-Bestrahlung von Glioblastomen

Institution: Department of Radiation Oncology, University Medical Center Mannheim
Applicant: Frank Anton Giordano

Contract is signed that launches the establishment of the "Else Kröner-Fresenius Center for Digital Health"
Press Release

Dresden creates ground-breaking interface between technology and medicine

Contract is signed that launches the establishment of the "Else Kröner-Fresenius Center for Digital Health" / EKFS is supporting innovation over a 10-year period with 40 million euro

Therefore, the aim of the present study was to assess the effect of empagliflozin on myocardial function in the human and murine myocardium and to identify the underlying mechanisms of action (together with PD Dr. Streckfuß-Bömeke).
Projekt

Pleiotropic effects of Empagliflozin in human and mouse myocardium

Institution: Universitätsklinikum Regensburg, Universitätsmedizin Goettingen (UMG) Herzzentrum
Applicants: Prof. Dr. Samuel Tobias Sossalla, PD Dr. Katrin Streckfuß-Bömeke

Structural variants can cause human disease by disrupting 3D genome organization.
Projekt

Identifying novel mechanisms for Huntington’s disease intervention by defining protein homeostasis of stem cells’

Institution: Center for Molecular Medicine Cologne (CMMC), University of Cologne
Applicant: Alvaro Rada-Iglesias

Homoarginine supplementation reduces infact size (white) in experimental stroke models (left) and higher homoarginine levels in patients are associated with increased survival rates after stroke (right)
Projekt

Clinical and experimental evaluation of homoarginine in stroke treatment

Institution: Department of Neurology, University Medical Center Hamburg-Eppendorf
Applicant: PD Dr. Chi-un Choe

Spontane pro-arrhythmische Kalziumfreisetzung in einer atrialen Herzmuskelzelle. Die neuartige Substanz „SEA“ verzögert das Einsetzen der Zelldepolarisation und wirkt damit zellulär antiarrhythmisch.
Projekt

In-vivo and in-vitro atrial dysfunction in heart failure with preserved ejection fraction

Institution: Charité Campus Virchow Klinikum
Applicant: Felix Hohendanner