Radiotherapy is a cornerstone of cancer treatment, yet its clinical effectiveness remains limited by damage to healthy tissue. Microbeam Radiation Therapy (MRT) represents a promising approach to overcome this fundamental limitation.

MRT delivers radiation in extremely narrow microbeams on a micrometer scale. Preclinical studies have demonstrated strong tumor control combined with exceptional normal tissue tolerance, resulting in a substantially enlarged therapeutic window.

The technological basis for clinical MRT has already been established in previous projects. The aim of this project is the regulatory preparation of first-in-human clinical trials. This includes the planning of preclinical safety and performance studies, the development of regulatory documentation, and early coordination with regulatory authorities and ethics committees.

By addressing these requirements, the project enables the translation of microbeam radiation therapy from advanced preclinical research into clinical evaluation and future patient care.