Die Else Kröner-Fresenius-Stiftung möchte die Medizinischen Fakultäten in Deutschland unterstützen, besonders interessierte und begabte Medizinstudenten für wissenschaftliche Forschungstätigkeit zu begeistern und zu gewinnen. Die Studenten sollen dabei die Möglichkeit erhalten, eine anspruchsvolle Promotion durchzuführen und den Beruf des Wissenschaftlers kennen zu lernen.
Die Preise sind mit jeweils 10.000 € für die private Verwendung des Preisträgers dotiert. Bewerben können sich geförderte Wissenschaftler* der Förderlinien Erst- und Zweitantragsteller, Else Kröner-Memorial-Stipendien und Else Kröner-Forschungskollegien.
With the support of the Else Kröner-Fresenius-Stiftung, we are unifying efforts to better describe immune cells in healthy individuals and also in people suffering from chronic infection, allergy, asthma, and inflammatory bowel disease. Our project focuses on lymphocytes, specifically the ones called CD4 T-lymphocytes. For the first time, CD4 T-lymphocytes appearing in these diseases over time are coordinately analysed in a deeper and extended manner.
Stress resilience belongs to the most important characteristics of a multicellular organism and its organs. Unfortunately, with progressive age, or as a consequence of certain pathologies, this trait becomes weaker, thus making an organ like the small intestine more vulnerable towards external insults. Work from the Ori lab is going to address how dietary restriction is influencing the age-associated resilience decline of the small intestine.
Social anxiety disorder is a common psychiatric disorder that is characterized by an intense fear of being embarrassed and negatively judged while in the company of other people, with a consequent avoidance of social situations.
The project is based on the investigation the poorly characterized multi-domain ciliopathy-protein MAPKBP1 (JNK-binding protein 1), which is located at ciliary basal bodies and centrosomes. Patients with mutations in this gene exhibit severe renal fibrosis and mild skelettal malformations. The overall aim of this project is to analyse the intracellular localization of MAPKBP1, to identify its interactome and explore its physiological roles in cellular signalling during the cell cycle.
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, is a group of immune-mediated disorders of the intestine, characterized by aberrant cytokine production by a multitude of immune cells in response to the microbiota. The interplay of these immune cell subsets (B cells, plasma cells, T cells and myeloid cell populations) is highly complex and poorly understood. We will apply a systemic approach to define an overall lymphocyte profile of immune cell subsets which contribute to a pro-inflammatory setting during chronic and acute IBD.
