Prostate cancer (PCa) affects millions of men worldwide and is a leading cause of cancer-related deaths. Current treatments induce major side effects including impotence, urinary incontinence, and musculoskeletal problems that negatively impact patients’ health-related quality of life, and in many cases fail, leading to the emergence of highly lethal forms of the disease. In this research program, the scientists outline their strategy to interrogate the potential use of a novel metabolic target to prevent and treat PCa. Importantly, they will investigate its inhibition as an approach to enhance the efficacy of hormonal therapy, as well as immunotherapy, which has so far had limited success in PCa. Therefore, this project will deliver new insights into the management of men with PCa.

Here you can get further information.