Abdominal Area, Kidneys & Pelvis
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Hemoproteins as therapeutic targets in acute kidney injury and regeneration

Institution: Hannover Medical School
Applicant: Dr. Robert Greite
Funding line:
First and Second Applications
Hemoproteins as therapeutic targets in acute kidney injury and regeneration

Acute kidney injury is one of the most serious complications after major surgery and organ transplantation — and targeted treatments are still lacking. This project focuses on hemoproteins: molecules released during cell damage that can place a heavy burden on the kidneys.

Using cutting-edge single-cell technologies, the scientists uncover how these processes harm individual kidney cell types and test new protective strategies in experimental models. Clinical data and patient samples from transplant and cardiac surgery cohorts complement the research.

The goal: to develop new biomarkers and innovative therapies for acute kidney injury.