Brain
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Binge Eating and neural variability

Institution: University clinics Tübingen, General Psychiatry and Psychotherapy with polyclinic, Section of Translational Psychiatry, Junior Research Group
Applicant: Dr. Nils B. Kroemer
Funding line:
First and Second Applications
Food has a rewarding effect for our brain. Within the framework of the project “Binge Eating and Neural Variability”, we are investigating the relationship between increased variability of the reward processing and the occurrence of binge eating episodes.

People who suffer from binge eating disorder experience recurrent episodes of binge eating. During these episodes, they consume an unusually large amount of food in a short amount of time and experience loss of control over eating. However, why such binge eating episodes occur is still largely unknown. This makes it difficult to develop targeted treatments.
In this project, we are investigating the brain mechanisms that give rise to the disorder. We hypothesize that the binge eating episodes are due to an increased variability in reward processing, which we will assess repeatedly over days. We will test this hypothesis using mathematical models based on behavioural and MRI measurements that are related to the processing of rewards.

Here you can get further information.