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Multiplexed complexome profiling
Projekt

Multiplexed complexomics to foster routine protein complex profiling in medical research and diagnostics

Institution: Universitätsklinikum Hamburg-Eppendorf
Applicant: Sergio Guerrero-Castillo

The project involves the preparation and execution of a first-in-man study to investigate the potential of novel small molecule ferroptosis inhibitors for the prevention of ischemia/reperfusion injury upon liver transplantation.
Projekt

Evaluation of ferroptosis inhibition for the treatment of ischemia/reperfusion injury upon liver transplantation: A first-in-man pilot study

Institution: Institut für Metabolismus und Zelltod, Helmholtz Zentrum München
Applicant: Dr. Marcus Conrad, Helmholtz Zentrum München

DKFZ-682 is a new inhibitor of the redox-buffer system regulated by thioredoxin. This system is particularly unstable in SCLC and thus enables the selectivity of the drug. The project promotes therapy optimization in a tumor model.
Projekt

Preclinical optimization of a therapy concept based on novel gold-DTC complexes for lasting control of small cell lung cancer

Institution: Deutsches Krebsforschungzentrum (DKFZ)
Applicant: Nikolas Gunkel

BsAb directed to PSMA and CD3 recruit T cells against tumor cells (A). To avoid “off target” activation and thus side effects (B), expression of the selected target antigen should be restricted to tumor cells.
Projekt

Drug substance production of the bispecific PSMAxCD3 antibody CC-1 to enable the conduct of a clinical study in patients with squamous cell carcinoma of the lung

Institution: Klinische Kooperationseinheit Translationale Immunologie, Deutsches Konsortium für Translationale Krebsforschung (DKTK), Deutsches Krebsforschungszentrum (DKFZ), Department für Innere Medizin, Universitätsklinikum Tübingen

Prof. Christoph Keplinger
Press Release

Professor Christoph Keplinger brings new generation of robots to Germany

Soft Robotics - artificial muscles that can heal themselves - opens new perspectives for medicine

EKFS-Jahresbericht 2019
Download

Annual Report 2019 (in German)

The Foundation's activities in review of the year.

Neuigkeiten aus dem HPI
Press Release

Start-Up PROVIREX: Innovative approach to curing HIV infection

Ascenion and Innovationsstarter Fonds Hamburg acquire equity in Hamburg start-up – innovative therapeutic approach enters clinical testing

Call of Proposals: Humanitarian Funding
Call for proposals To

7th Funding Round Hospital Partnerships

The next funding round will be open from 25th of May until 22nd of June 2020.

Aktivitäten von Ärzte für Madagaskar im Bereich Müttergesundheit
Press Release

Digitales Gesundheitssparbuch

Neue Wege für den Schutz vor medizinischer Verarmung