Currently funded projects

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Dose expansion of ProSperA_CC-1: Phase I/IIa study to evaluate the safety, tolerability and preliminary efficacy of the bispecific PSMAxCD3 antibody CC-1 in men with biochemical recurrence of prostate cancer

Institution: Department of Medicine, Clinical Collaboration Unit Translational Immunology, University Hospital Tübingen
Applicant: Dr. Jonas Heitmann
EKFS funding line: Translational Research

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Detection of nicotinamide adenine dinucleotide (NAD) in cells and blood plasma

Institution: Charité – Universitätsmedizin Berlin, Experimentelle Chirurgie, Campus Virchow-Klinikum
Applicant: PD Dr. med. Felix Krenzien
EKFS funding line: Translational Research

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LOGIBODY – logic-gated antibodies for cancer immunotherapies

Institution: Prof. Dr. Hendrik Dietz – Lehrstuhl für Biomolekulare Nanotechnologie, Technische Universität München
Applicants: Dr. Klaus F. Wagenbauer, Dr. Benjamin Kick and Dr. Jonas J. Funke
EKFS funding line: Translational Research

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Translational development of a novel immunohematology technology for detection, specification and pre-analytical depletion of irregular and medicinal antibodies against red cell, platelet and neutrophil antigens

Institution: DRK-Blutspendedienst Baden-Württemberg-Hessen
Institut Frankfurt am Main und Institut für Transfusionsmedizin und Immunhämatologie
Fachbereich Medizin, Johann-Wolfgang-Goethe Universität Frankfurt
Applicant: Prof. Dr. Halvard Bönig
EKFS funding line: Translational Research

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Precision immunotherapy: Mutation-specific TCR-T cell therapy for MyD88L265P mutated lymphoma – GMP-grade vector production and establishment of TCR-T cell manufacturing

Institution: Medizinischen Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunologie, Charité – Universitätsmedizin Berlin Campus Benjamin Franklin
Applicant: PD Dr. med. Antonia Busse
EKFS funding line: Translational Research


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Upscaling the antibody-protamine-nanocarrier mediated siRNA therapy: Preparation of a clinical phase I study in patients with acute myeloid leukemia (AML)

Institution: Medizinische Klinik A, Labor für Molekulare Hämatologie und Onkologie, Universitätsklinikum Münster
Applicant: Dr. rer. nat. Sebastian Bäumer
EKFS funding line: Translational Research

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Development of an interactive app for structured prehabilitation before major surgery – PROTEGO MAXIMA

Institution: Klinik für Allgemein-, Viszeral-, Transplantations- und Thoraxchirurgie, Universitätsklinikum Frankfurt
Applicant: Prof. Dr. Andreas Schnitzbauer
EKFS funding line: Translational Research

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The Relaxin Receptor 1 for Treatment of Heart Failure

Institution: Medizinische Klinik (Krehl-Klinik), Zentrum für Innere Medizin, Klinik für Kardiologie, Angiologie und Pneumologie, Innere Medizin III, Heidelberg
Applicant: Prof. Dr. med. Philip Raake
EKFS funding line: Translational Research

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Low molecular weight polysialic acid as glycome-based biologic for the therapy of dry age-related macular degeneration

Institution: Institut für Rekonstruktive Neurobiologie, Medizinische Fakultät, Rheinische Friedrich-Wilhelms-Universität Bonn
Applicant: Prof. Dr. med. Harald Neumann
EKFS funding line: Translational Research

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alphaSEPT – Development of a next-generation immunomodulating biopharmaceutical for the causal treatment of sepsis

Institution: TU München Department Chemie und Institute for Advanced Study
Applicant: Prof. Dr. Matthias J. Feige
EKFS funding line: Translational Research